Posted by ed_uk2010 on March 30, 2018, at 16:48:54
In reply to Tianeptine, posted by beckett2 on March 30, 2018, at 10:16:01
> Day three of Tianeptine powder, and today, a slightly brighter mood.
>
> Has anyone here tried or taking it?Never taken it personally.
It was initially claimed to be some form of serotonin re-uptake enhancer, which didn't entirely make sense. It wasn't based on proper evidence and was probably nonsense!
More recent evidence suggests that it acts as some form of agonist or modulator at mu-opioid receptors. This sounds more plausible.
https://www.ncbi.nlm.nih.gov/pubmed/28303899
In spite of what it says above, there are plenty of reports of tolerance and withdrawal after high doses of tianeptine have been used. I would therefore say it's something which should be dosed very carefully, to avoid risks.
poster:ed_uk2010
thread:1097839
URL: http://www.dr-bob.org/babble/20180212/msgs/1097855.html