Posted by JohnBoy2000 on March 11, 2018, at 15:15:20
I've cycled through most classes of drugs, and the primary noradrenergic drugs.
Bupropion, reboxetine - and the final selective NA drug - Atomoxetine.
I've also had Lofepramine, which is like the UK's desipramine - being a prodrug to it.
I didn't respond well to it - could only tolerate lowest dose.However - the only real outstanding possible useful drug I haven't tried is MAPROTILINE.
Now - I've done a search on this forum on it - and there is some feedback; cause, it being an old drug, it is extremely difficult to find anything on it.
It's been taken off most markets - but it can be source from Belgium or something.
That being said - being a potent anti-histamine, it would have to be taken at night time.
I already take Mianserin, the alpha 2 blocker and NA drug, at night time.
Which may cause excessive night time activation - I couldn't take Lofepramine at night time for that reason.
Which leads me to my question.Does anyone have current or past experience with Maprotiline?
I've read in other posts that - its sedation can extend to the daytime?
I definitely don't find that with Mianserin.It is used in agitated depression, for its sedative properties, which is not what I would require it for.
Atomoxetine is great for energy for me - not at all sedating.
So - any insights?
poster:JohnBoy2000
thread:1097284
URL: http://www.dr-bob.org/babble/20180212/msgs/1097284.html