Posted by Christ_empowered on November 13, 2017, at 16:14:00
In reply to Re: Does Zyprexa reduce serotonin?, posted by farshad on November 13, 2017, at 16:04:04
hi. my -very- basic understanding of this is that blocking a receptor just means that the drug prevents the serotonin from acting on that receptor. All known antipsychotics/tranquilizers block D2 receptors, for instance. The dopamine still courses thru the brain (clearly, I'm --not-- an expert, LOL), but the drug prevents the dopamine from acting (as much...) on the receptor, which causes a change in mental state and (often..) behavior.
The brain adapts to psych drugs, over time. That's why in long term antipsychotic/tranquilizer treatment, you see "upregulation" of D2 receptors. The drug blocks the D2 receptors, and the brain responds by changing structure in response to the (artificial, drug-induced) D2 blockade. Problem there is...that might actually -create- more long-term disability, vulnerability to psychosis, etc.
ok. Hopefully, SLS, linkadge, or...somebody...will respond w/ some more detailed information.
poster:Christ_empowered
thread:1095859
URL: http://www.dr-bob.org/babble/20161215/msgs/1095865.html