Posted by SLS on November 12, 2017, at 21:06:05
In reply to Residual anhedonia on Parnate, posted by pedr on November 12, 2017, at 8:30:05
My personal experience with MAOIs is that Parnate can leave residual anhedonia, even at high dosages. Nardil is a stronger mood-brightener and is better at treating anhedonia. I found that adding nortriptyline helps with anhedonia when added to Parnate. Desipramine did not. However, it often happens that someone is inadequately treated with Parnate and never reaches a therapeutic level. You will find some variability in the literature, but I would say that the dosage range lies between 40-80 mg/day. You really can't evaluate the amount of residual anhedonia that Parnate leaves until it is titrated to a dosage that gives maximal effect, even if only a partial response. I'm sorry that your doctor is resistant to adding a stimulant. You could try to find literature that suggests that adding either nortriptyline or desipramine is not only safe to add to a MAOI, but might even mitigate the tryramine pressor response. Try Google or PubMed.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1095844
URL: http://www.dr-bob.org/babble/20161215/msgs/1095850.html