Posted by porkpiehat on October 17, 2017, at 22:16:43
I copied this from Social Anxiety report so I didn't have to retype:
Yesterday I took 30 mgs parnate.
Today I got my marplan. I am used to the lift from parnate that I need to get me through my evening work, so I took 10 mgs parnate and then 10 mgs marplan, and later another 10mg.
I have no idea how marplan binds to and disables the monoamine oxidase, but people have jumped straight from parnate to nardil so I'm guessing I'm ok (plus my doses are so low to begin with). It could bind to the existing MAO that's already disabled or it could target still active ones. In the former it would take a while for marplan to build to therapeutic dose, in the latter it should be quicker.
I almost like the idea of continuing with 10mgs parnate because it has a short-lived amphetamine effect that my body is used to but not enough to create a dopamine or NE crisis because it is built into parnate which is a MAOI. I will ask dr. Gillman but otherwise switch to a 30mg marplan course tomorrow.
After the parnate I had the typical bout of bounce followed by trouble oversharing. this diminished after the marplan, in which case I started thinking about non-work things which haven't exited me in a while...almost to the point of being bored with work and forcing myself into focusing..
I have already noticed the absence of the lion's share of parnate's stimulant effect, in that the compulsive urge to drink and smoke never came tonight. Also I desired to visit a friend in public and instead of feeling nervous and giving people wan smiles and looking away I gave full smiles and wasn't distant.
Still early on. Not sure what is what or if marplan will have any noticable effect in the near future.Fingers crossed. Will continue to use cocktail of trazodone and gabapentin for sleep for now.
Cheers. Chime in with thoughts or use my thread for reference :)
poster:porkpiehat
thread:1095475
URL: http://www.dr-bob.org/babble/20161215/msgs/1095475.html