Posted by PeterMartin on October 2, 2017, at 15:41:38
In reply to Deplin for lamictal side effects?, posted by porkpiehat on October 2, 2017, at 14:02:33
> My new doctor thinks that my negative response to long-term lamictal (cognitive issues, sleep, rumination, muscle spasm) could be related to reduced methylfolate (??) and that Deplin would reverse it
>
> I've never heard about this and my research on the relationship isn't turning up much. Any other Lamictal takers hear this before?Definitely don't add deplin to Lamictal.
There was double blind study published in 2016 that found folate can nullify the effects of Lamotrigine.
Pretty sure this is the first time it was reported but I would print that and show your doctor.
http://www.sciencedirect.com/science/article/pii/S2215036615004502
Good site to search for info is scholar.google.com btw.
poster:PeterMartin
thread:1095178
URL: http://www.dr-bob.org/babble/20161215/msgs/1095180.html