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Re: Are there any 5ht1a Inverse Agonists?

Posted by linkadge on July 28, 2017, at 10:43:22

In reply to Re: Are there any 5ht1a Inverse Agonists? » Hello321, posted by SLS on July 26, 2017, at 19:51:35

No, there really are no selective inverse agonists / antagonists at 5-ht1a. I assume you've tried propranolol / pindolol, as they (supposedly) have some antagonist activity.

Transcranial magnetic stimulation supposedly down regulates 5-ht1a, which would have the same net effect as an antagonist.

Linkadge


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