Posted by SLS on October 18, 2016, at 5:53:37
In reply to Re: Doctor thinks I need a phenylpiperazine? Help!?, posted by Jonhed on October 16, 2016, at 16:52:55
Did you see the article I posted to you regarding the treatment of akathisia?
Saphris is less likely to produce akathisia at the same rate as Abilify. For me, the mild akathisia I experienced with Abilify disappeared completely withing a week. I started at 20 mg/day. If Abilify (aripiprazole) helps improve symptoms, and you are looking for a replacement drug, you might try Rexulti (brexpiprazole) instead. On paper, it should produce akathisia at a reduced rate. I haven't seen enough people on it to know for sure. I would still give Saphris a try if you haven't already. If it is going to work for depression, it should do so within a week provided you are taking a therapeutic dosage.
Regarding the article I posted, it is proposed that drugs that block serotonin 5-HT2a receptors can act to reduce akahisia. Abilify is not very potent at blocking these receptors, so you might try adding low-dose Remeron (mirtazapine) as a remedy for Abilify-induced akathisia.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1092616
URL: http://www.dr-bob.org/babble/20160928/msgs/1092653.html