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Re: Doctor thinks I need a phenylpiperazine? Help!? » Jonhed

Posted by SLS on October 18, 2016, at 5:53:37

In reply to Re: Doctor thinks I need a phenylpiperazine? Help!?, posted by Jonhed on October 16, 2016, at 16:52:55

Did you see the article I posted to you regarding the treatment of akathisia?

Saphris is less likely to produce akathisia at the same rate as Abilify. For me, the mild akathisia I experienced with Abilify disappeared completely withing a week. I started at 20 mg/day. If Abilify (aripiprazole) helps improve symptoms, and you are looking for a replacement drug, you might try Rexulti (brexpiprazole) instead. On paper, it should produce akathisia at a reduced rate. I haven't seen enough people on it to know for sure. I would still give Saphris a try if you haven't already. If it is going to work for depression, it should do so within a week provided you are taking a therapeutic dosage.

Regarding the article I posted, it is proposed that drugs that block serotonin 5-HT2a receptors can act to reduce akahisia. Abilify is not very potent at blocking these receptors, so you might try adding low-dose Remeron (mirtazapine) as a remedy for Abilify-induced akathisia.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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