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Effexor combo/update

Posted by porkpiehat on October 14, 2016, at 13:33:37

Coming up on Month 2 of effexor. Ive ended up on quite the combo that doesn't seem super sustainable:

Effexor 37.5
Lamictal 100mg
.5 mgs Klonopin
10-30 mgs propranolol
10 mgs Vyvanse

The day before I started effexor I was just sooo sad and socially uncomfortable, with occasional disociative and panic episodes at night. No drive. Could connect emotionally with television but not people.

Effexor immediately made me feel zoned out but the intense sadness started to lift. I started taking the propranol to help take the edge off the irritability that came in the afternoons. Sex drive gone.

up to about 60 mgs I felt so frigid and annoyed by other people it was creating its own kind of social anxiety because I hate having to deal with them. Also tired all day and unable to sleep through the night

Added Vyvanse to help brighten my mood and engage me and it helps, but I need to keep up with the propranolol, lamictal, and klonopin to keep me from getting too overstimulated and drinking/fiending.

I can concentrate and read in a way I can't remember and talk with self possession (I can actually see myself handling an interview for grad school). I'm afraid to f*ck with the this but Gosh darn do I feel COLD and intolerant of everything. I would say I'm not "depressed" and suicidal, but I don't feel like I'm an active part of humanity and I never feel lighthearted. Frankly everyone could burn and I probably wouldn't care. Even music, which I live for, kind of gets under my skin.

But I am very good at work and homework and I'll probably crush the GREs...but I don't see myself getting through grad school feeling so detatched, almost sociopathic.

I'm also not sure if this combo is terribly safe.

I tried "just lamictal" sometimes with wellbutrin, for 6 months or so but it didn't cut it after 8 years of celexa.

I probably feel about as numb on 37.5 mgs of effexor as I did a high dose of Prozac, but there was a sense of happiness then at least.

People keep suggesting other NE-active drugs to replace the effexor (cymbalta, etc), but based on my experience with others (WB, Serzone, desipramine and cymbalta for about two days), I think that might be responsible for the detatchment and gray feeling. And the irritability. And the focus, unfortunately.

Trauma and/or bipolar II may complicate.

has this been anyone elses' experience?


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poster:porkpiehat thread:1092614
URL: http://www.dr-bob.org/babble/20160928/msgs/1092614.html