Posted by Mark25 on July 24, 2016, at 18:57:52
Do you think this combo is safe?
Drug interaction checkers state MAOIs shall not be combined with trazodone, but quite a few people take those two meds without problems.
Also the German manufacturer of tranylcypromine (Aristo Pharma) says the combination is safe, as long as the MAOI is added to existing trazodone therapy. This study confirms it: http://www.ncbi.nlm.nih.gov/pubmed/2365668
Aristo Pharma states that combining tranylcypromine with atypical antipsychotics is OK. And in fact, olanzapine has been used to treat serotonin syndrome.
But there a rare reports of serotonin syndrome following treatment with olanzapine (and other serotonergics).
Quite confusing.
poster:Mark25
thread:1090832
URL: http://www.dr-bob.org/babble/20160713/msgs/1090832.html