Re: Does Rexulti affect less receptors then Abilify?

Posted by SLS on May 1, 2016, at 16:23:52

In reply to Re: Does Rexulti affect less receptors then Abilify? » revv33, posted by J Kelly on May 1, 2016, at 12:44:54

Rexulti (brexpiprazole) is less of a D3 dopamine partial receptor agonist than is Abilify. If I understand correctly, there should be less akathisia associated with its use. Rexulti is more active at serotonin 5-HT1a receptors than is Abilify. In addition, Rexulti blocks certain norepinephrine alpha-2 receptors. I don't know what the end result would be of these actions. I guess Rexulti acts as a sort of dopamine-serotonin system modulator.

- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.
- George Bernard Shaw

Thread

Does Rexulti affect less receptors then Abilify? revv33 5/1/16
Re: Does Rexulti affect less receptors then Abilify? » revv33 J Kelly 5/1/16
Re: Does Rexulti affect less receptors then Abilify? revv33 5/1/16
Re: Does Rexulti affect less receptors then Abilify? revv33 5/1/16
Re: Does Rexulti affect less receptors then Abilify? » revv33 J Kelly 5/1/16
Re: Does Rexulti affect less receptors then Abilify? revv33 5/1/16
Re: Does Rexulti affect less receptors then Abilify? » revv33 J Kelly 5/1/16
Re: Does Rexulti affect less receptors then Abilify? crabcakebenny 5/1/16
Re: Does Rexulti affect less receptors then Abilify? SLS 5/1/16

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