Posted by Robert_Burton on April 5, 2016, at 7:29:52
In reply to Re: codeine and parnate?, posted by SLS on April 4, 2016, at 7:30:03
> http://bja.oxfordjournals.org/content/95/4/434.full
>
> It is a difficult decision to make.
>
>
> - ScottExcellent citation. Note that the relevant finding is: "The phenylpiperidine series opioids, pethidine (meperidine), tramadol, methadone and dextromethorphan and propoxyphene, appear to be weak serotonin re-uptake inhibitors and have all been involved in serotonin toxicity reactions with MAOIs (including some fatalities). Morphine, codeine, oxycodone and buprenorphine are known not to be SRIs, and do not precipitate serotonin toxicity with MAOIs."
There is, hence, no possibility of of SS arising from codeine co-administration with an MAOI.
poster:Robert_Burton
thread:1087824
URL: http://www.dr-bob.org/babble/20160331/msgs/1087846.html