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Re: xanax and intermittent withdrawal symptoms » Phillipa

Posted by Hugh on January 6, 2016, at 10:52:18

In reply to Re: xanax and intermittent withdrawal symptoms » paulb, posted by Phillipa on January 4, 2016, at 9:38:44

> Been on benzos for over 45 years. Only take both xanax .75mg at night and divided dose of valium also. And about 10 years ago they stopped just relaxing me. Now just put me to sleep. Never take them during the day and remain anxious. Also the 25mg of luvox & .25mg of lexapro. So I remain anxious throughout the day and don't drive any longer either. Is there a reason for this?

The following quote is from http://www.benzo.org.uk/manual/bzcha01.htm

Tolerance is a phenomenon that develops with many chronically used drugs (including alcohol, heroin and morphine and cannabis). The body responds to the continued presence of the drug with a series of adjustments that tend to overcome the drug effects. In the case of benzodiazepines, compensatory changes occur in the GABA and benzodiazepine receptors which become less responsive, so that the inhibitory actions of GABA and benzodiazepines are decreased. At the same time there are changes in the secondary systems controlled by GABA so that the activity of excitatory neurotransmitters tends to be restored.


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