Posted by SLS on October 24, 2015, at 16:25:36
In reply to Fluvoxamine Abilify interaction, posted by MuseMemento on October 24, 2015, at 14:49:42
> I'm currently taking 300 mg fluvoxamine and 10 mg abilify. Prior to taking the fluvoxamine, I was on clomipramine at a high dose along with 20 mg of abilify. I lowered the abilify specifically because of the inhibition of cyp3a4 by fluvoxamine but I've noticed decreased efficacy. Is fluvoxamine a strong inhibitor of cyp3a4 or is it rather mild? Could I try raising the abilify up to 15 mg and see the response?
I think fluvoxamine is a rather strong inhibitor of CYP3A4.
People sometimes go up to 30 mg/day of Abilify. So, even if fluvoxamine were to cause the level of Abilify to double, you would still be safe at 15 mg/day. If you were to go too high with the dosage of Abilify, you would feel somewhat less motivated and numb cognitively. I think it is hard to become toxic on Abilify. The ideal dosage of Abilify for me is 10 mg/day. If I double the dosage, I experience the side effects I described, but they are rather mild.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1083671
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