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Re: Would a 5ht1a Full Agonist VS Partial Agonist

Posted by SLS on August 19, 2015, at 14:13:23

In reply to Would a 5ht1a Full Agonist VS Partial Agonist, posted by Hello321 on August 19, 2015, at 13:58:10

> You might have heard on the news about the new pill, Fkibanserin, that was just approved for female sexual dysfunction. Ive read about how it works as a full agonist at the 5ht1a postsynaptic receptor, unlike mood meds like Buspar and Viibryd that work as a partial agonist at it. Flibanserin was actually intended to be a depression med when its development first began, but eventually switched to bbeing developed for sex problems. It works on the same receptors that mood meds target.
>
> Anyway, might a full agonist be better for mood problems than the partial agonists we have today? Might it actually be better for anxiety than Buspar?

I believe Brintellix (vortioxetine) is closer to being a full agonist than a partial agonist.


- Scott


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I dream of things that never were and ask why not.

- George Bernard Shaw

 

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URL: http://www.dr-bob.org/babble/20150806/msgs/1081519.html