Posted by phidippus on August 5, 2015, at 10:58:46
In reply to PDE4 inhibitors?, posted by SLS on July 22, 2015, at 9:06:22
Mesembrine, an alkaloid from the herb Sceletium tortuosum
Rolipram, used as investigative tool in pharmacological research
Ibudilast, a neuroprotective and bronchodilator drug used mainly in the treatment of asthma and stroke. It inhibits PDE4 to the greatest extent, but also shows significant inhibition of other PDE subtypes, and so acts as a selective PDE4 inhibitor or a non-selective phosphodiesterase inhibitor, depending on the dose.
Piclamilast, a more potent inhibitor than rolipram.[24]
Luteolin, supplement extracted from peanuts that also possesses IGF-1 properties.[25]
Drotaverine, used to alleviate renal colic pain, also to hasten cervical dilatation in labor
Roflumilast, indicated for people with severe COPD to prevent symptoms such as coughing and excess mucus from worsening[26]
Apremilast, used to treat psoriasis and psoriatic arthritis.Eric
poster:phidippus
thread:1080700
URL: http://www.dr-bob.org/babble/20150629/msgs/1081022.html