> > This seems like a promising treatment for mania, psychosis, and possibly mixed states / insomnia.
> >
> > It can induce depression (in higher doses).
> >
> > Google this substance - but caution, it depletes monoamines (mainly dopamine and norepinephrine).
> There is some old literature about the use of reserpine for various psychotic states. It didn't seem to garner much support by the medical community as a clinical treatment. I don't remember why. One rather interesting proposal for the treatment of depression was to administer reserpine first, followed by a TCA. Perhaps it somehow changes the function of storage vesicles. That's just a wild guess.
>
> Medline / PubMed isn't working for me right now. You should find some titles, but probably not necessarily the abstracts. I'll check out Google.
I found some stuff on Google that suggested using a tricyclic first as a pretreatment, followed by reserpine. This is the opposite order of what I had indicated, but my memory sucks.
https://www.google.com/?gws_rd=ssl#q=reserpine+depression+tricyclic
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