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Re: SSRI withdrawal symptoms really scare me! » fido

Posted by Robert_Burton_1621 on March 2, 2015, at 17:51:52

In reply to Re: SSRI withdrawal symptoms really scare me!, posted by fido on March 2, 2015, at 16:55:41


> Go to drugs.com and search for adderall + ssri. They warn you of serotonin syndrome. I also checked other medical interaction websites they also mention the risk. Also, there are REAL cases of SS when mixing adderall + ssri/snri.
> I don't really care what Gillman writes. The fact that SS happened under this combo means that there is a risk!

Drugs.com will say incorrectly that many combinations can cause serotonin syndrome. It says mixing mirtazapine with venlafaxine carries the "major" risk of serotonin syndrome! This is just erroneous. Mirtazapine has been used to treat serotonin syndrome.

I feel, from my perspective, that it is better to take into consideration well-evidenced information by people who have expertise in this particular area, than to rely reflexively on sites like drugs.com, but that is of course a matter for you and your doctors.

Amphetamines at the right dose are so low in their serotonergic potential that the risk, if any, is low. But it seems that your current conditions and the inadequate experiences you've had with psychiatrists may be predisposing you to overestimate any risks and underestimate the relative efficacy of potential treatment options.

> I tried anafranil and 75mg were already too much. It made my heart race. This is why my doc said that I can forget about other TCA cause they all would do the same cause they all have the same antichol. side effects.

It is not correct to advise that all TCAs have the same degree of side-effects as clomipramine. Clomipramine is usually very effective for OCD but it carries a high degree of TCA-related side-effects. Nortriptyline does not carry them to the same extent, much less.

> I also dont know if a combo like SSRI + nortriptyline would be better than SSRI + wellbutrin or SSRI + strattera. Strattera scares me somehow. I read it can make you suicidal.

The combination of SSRI and strattera may be worth trying. In regards to suicide, most anti-depressants now carry generic advice warning about an increase in suicidal thoughts.

> But nortrip on the other hand would have much more side effects as a TCA. Wellbutrin at least had no side effects.
>

Nortriptyline has fewer side-effects and to a lesser degree than clomipramine, for instance.



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