Posted by ed_uk2010 on February 23, 2015, at 11:54:57
In reply to Re: can moclobemide be combined with desipramine or, posted by TriedEveryMedication on February 22, 2015, at 18:51:11
> According to the article below, NRIs like desipramine completely block tyramine update and the pressor effect.
>
> that is a good thing when dealing with MAOIs, right?Yes, it is. I doubt that very low doses of desipramine would be enough to completely block the effect, but it might be reduced.
> Do you think it is preferable to start one of the drugs first then add the other?
It used to be claimed you should add an MAOI to a TCA, rather than the other way around. I'm unsure of the rationale for this, and it might not apply to low dose desipramine anyway.
poster:ed_uk2010
thread:1076938
URL: http://www.dr-bob.org/babble/20150223/msgs/1077021.html