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Re: What is OCD?

Posted by Bill82 on February 17, 2015, at 14:15:14

In reply to Re: What is OCD?, posted by phidippus on February 16, 2015, at 1:31:13

Little off topic I guess? But anyways I just learned about PKa and PKc and their involvement in OCD. The article below describes how PKc effects 5ht uptake in ocd vs controls, with evidence supporting 5ht uptake is depressed in ocd, and the PKc agonist in both groups depressed uptake further, although more significantly in OCD subjects. Also other studies have shown PKc to be hyperactive in ocd and PKa to be hypo active. Reading up in the two and their effects in the brain it shows that their effects are primarily on the 5ht system primarily being 5ht2a. Perhaps level of cellular function in a more accurate targeting method could be the future if OCD? Just thought id share because it gave me some hope today, just got an ivig infusion and ocd is aweful/seemingly more real and that I don't care. Anyways let me know if you have any thoughts.


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poster:Bill82 thread:1075804
URL: http://www.dr-bob.org/babble/20150129/msgs/1076833.html