Posted by ed_uk2010 on January 18, 2015, at 15:56:40
In reply to Re: Splitting pills. Reliable or not? (@Ed and others), posted by Zyprexa on January 16, 2015, at 22:25:55
>I even split 'er' pills. just don't crush them.
Some ER/modified-release tablets are designed to be split in half (and are scored). This type of tablet often relies on the drug being distributed throughout a polymer matrix which releases drug gradually.
On the other hand, other ER tablets will no longer be ER when split in half. An example is ER tablets which rely on an insolube casing containing a small hole to let the drug release gradually.... such tablets will become 'immediate release' when split.
poster:ed_uk2010
thread:1075154
URL: http://www.dr-bob.org/babble/20150102/msgs/1075243.html