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Re: Mutiple mechanism with Zyprexa and some atypicals » Lamdage22

Posted by ed_uk2010 on January 18, 2015, at 15:15:25

In reply to Re: Mutiple mechanism with Zyprexa and some atypicals, posted by Lamdage22 on January 18, 2015, at 13:50:31

>Doesnt high prolactin mean low testosterone?

I assume you are a man? Elevated prolactin in men often causes symptoms if tesotesterone levels are suppressed as a result. This is common if prolactin is very high, but not if it's marginally elevated. High prolactin causes symptoms in women more frequently than it causes symptoms in men. This is because it can induce lactation, disrupt the menstrual cycle and reduce oestrogen levels. Women who are not lactating normally have similar prolactin levels to men. In men, most symptoms of hyperprolactinaemia, if they occur at all, are due to moderately reduced testosterone levels. Reduced libido and erectile dysfunction can occur if testosterone levels are reduced (these symptoms are not permanent, they will disappear with treatment or a change in meds). Don't worry about it in advance, it may not happen.

If your prolactin is high, and you are a man, you can also have a blood test to check your testosterone. Gonadotrophins may also be checked. Testosterone is not usually measured in women. Aripiprazole (Abilify) is effective against elevated prolactin caused by most antipsychotics.... but is not very effective against amisulpride and you don't tolerate the side effects anyway. If you do experience high prolactin and blood tests also show low testosterone (assuming you're a man), testosterone supplementation could be prescribed if you have symptoms as a result. Testosterone gel might be suitable eg. the one you apply once daily to an area of skin, and it's absorbed into your body gradually over several hours. Mildly reduced testosterone not causing symptoms doesn't necessarily require any treatment. The herbal treatment I mentioned has been shown to be effective against the symptoms of hyperprolactinaemia... as well as improving the blood results. Sexual function was improved. I just don't know how easy it is to buy the correct product.

In the long term, obesity and diabetes caused by drugs like Zyprexa may cause more harm than the hormonal disturbances which are common with amisulpride. Diabetes causes erectile dysfunction very frequently, for example.

 

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