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Re: Sigma-1 Cannabinoid Interaction - Study » linkadge

Posted by SLS on January 9, 2015, at 21:40:14

In reply to Sigma-1 Cannabinoid Interaction - Study, posted by linkadge on January 9, 2015, at 20:39:49

> http://www.medicalnewstoday.com/releases/287733.php
>
> The study seems to suggest that sigma-1 agonists can prevent the NMDA hypofunction that occurs with cb-1 agonism.
>
> In other words, in cases where there is excessive cannabinoid signalling (causing glutamate hypofunction) sigma-1 agonism can reverse / offset this.
>
> This possibly explains some of the effect of fluvoxamine on psychotic depression.
>
> Linkadge


Nice work.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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URL: http://www.dr-bob.org/babble/20150102/msgs/1075015.html