Posted by hello123 on January 8, 2015, at 17:54:49
this is a bit of a technical question, but ive read that increasing Norepinephrine can have a downstream effect of increasing Dopamine. How does this increase in Dopamine actually occur? ive tried finding an article describing it, but cant find anything on Pubmed.
ive had a feeling NRI's have an indirect effect on Dopamine after my experience with a few SNRI Antidepressants, but my experience felt more like a severe *decrease* in Dopamine instead of an increase. After about 3 days on SNRI's ive experienced a severe decrease in ability to feel pleasure thats very different in the numbing effect an increase in Serotonin has. But the decrease in pleasure ive experienced from SNRI's has caused me to stop the med after the length of time that is typical for a full med trial. And my pdoc prescribed Strattera for Depression today and im hoping i will be able to give this a full trial. Does anyone have exoerience with meds that increase Norepinephrine causing worse Depression the first few weeks, with mood improvements after that?
poster:hello123
thread:1074965
URL: http://www.dr-bob.org/babble/20150102/msgs/1074965.html