Posted by SLS on July 15, 2014, at 10:20:44
In reply to Re: Intranasal ketamine - Anyone?, posted by babbler20 on July 13, 2014, at 23:51:19
> Sorry you aren't doing well SLS.
Thanks, Babbler. My sense of hope and positive outlook are deteriorating.
> I know we have both been at this for a while. From what I've heard Ketamine works for some, but like with any other anesthetic there are only so many times you can use it before it becomes dangerous to continue using it.
I wasn't aware of that. What are some of the dangers attendant with the long-term use of ketamine?
> I don't think this is the answer for us, but one of the substances they are working on bringing to market that is derived from ketamine, could be our answer.
You are probably right. It is proposed by some that one of the major metabolites of ketamine, known as HNK, is capable of exerting an antidepressant effect without the complications of the anesthetic and psychotomimetic effects of ketamine. It works via nicotinic alpha-7 receptors and doesn't affect the NMDA receptor at all. Unfortunately, it might take many years before such a compound could be developed and marketed.
Thank you for your concern. Good thoughts heading your way...
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1068237
URL: http://www.dr-bob.org/babble/20140609/msgs/1068342.html