Posted by Louisiana Sportsman on July 5, 2014, at 15:03:06
In reply to New strategy needed, posted by Linkadge on July 1, 2014, at 16:14:35
You're very smart. Linkadge. I notice this from your posts around here.
Are these the only two medications you take? I myself take a NaSSA + SSRI: Remeron 45mg., Zoloft 50mg. along with other medications.
I imagine you chose Luvox because it is a SSRI and sigma-1 receptor agonist. I imagine Remeron was chosen due to its novel mechanism of action. In theory, it is an expert combo. But in real life, I can see how it could be sedating.
Mirtazapine is potent. I imagine it is the culprit. See how you feel on Luvox monotherapy for a second. It is probably causing some sedation too. If it is manageable without mirtazapine:
"fluvoxamine + nortriptyline: safe, but not recommended, because the only CYP450 isoform fluvoxamine does not inhibit is 2D6."
On paper, try nortriptyline. It would compliment Luvox well based on theory.
In reality, bupropion and Luvox would be your best bet. Mirtazapine and bupropion sounds good too. The NDRI is here for the obvious stimulatory effect.
Beyond this point, you are asking me to pick two medicines out of the blue with no information. Umm, Latuda and Lyrica. Try that for real if you're only gonna take two medicines and they are going to be brand new, those I suggest.
Good luck with everything, man.
poster:Louisiana Sportsman
thread:1067722
URL: http://www.dr-bob.org/babble/20140609/msgs/1067944.html