Posted by porkpiehat on June 10, 2014, at 12:18:42
In reply to Re: at 3+ weeks, posted by sk85 on June 2, 2014, at 15:34:47
> To conclude my vortioxetine trial so far:
>
> Pros:
> -cognitive performance quite much improved
> -no insomnia (I get that with SSRIs)
> -no sexual SEs
> -lowered performance and general anxiety
> -no changes in appetite
>
> Neutral:
> -slight irritability
>
> Cons:
> -unimpressive antidepressant effect
> -expensive
> -again anhedonic (as mentioned above may have nothing to do with Brintellix)
>
> So overall I'm feeling like I need to increase the dose (very expensive idea) or augment with something to help with mood. Before Brintellix I had ravingly impressive AD effects with sertaline+pramipexole but became completely insomniac on it (also check out: http://www.ncbi.nlm.nih.gov/pubmed/16963794). I might consider trying this time vortioxetine and prami.
>
> I also think I need to give this current dose still few more weeks, at least until 6 weeks. I also suspect I still might have some unaddressed bipolar symptoms that I'm going to take up with my pdoc next meeting. It's really difficult to pinpoint a mild bipolar case.
>
>
This is my experience exactly. By adding just 5mgs of Celexa back to the mix I am finding a returned energy to do things and interact with people. I've lowered Brint. by 5mgs in the morning. Vyvanse as needed.My doctor wants to switch me to Viibryd, thinking it has fewer post-synaptic actions that could be blanding me out and feeling isolated and uninterested around people.
Although a lot of people would term this mix as "voodoo," I'm hesitant to switch completely over to the Viibryd.
poster:porkpiehat
thread:1065908
URL: http://www.dr-bob.org/babble/20140609/msgs/1066763.html