Posted by klein on April 24, 2014, at 23:04:23
In reply to Re: Cymbalta vs Pristiq, posted by LouisianaSportsman on April 24, 2014, at 9:58:18
> Not a bad choice, but I think that if Effexor was pretty good, and you're looking for something better -- without the side effects and histamine antagonism of those yet effective, and not a bad choice, tetracyclic antidepressants -- then Pristiq isn't so bad, considering you did good on Effexor.
>
> I did Effexor XR 75mg. when I was titrating off of Pristiq so I could use the beads, and I notice that it was significantly inferior and I had sexual side effects I didn't have on Pristiq.Remeron is my safety net. Like that other website says (I dunno if it's ok to quote it), Remeron pulls you out of the darkest, deepest depression like no other med will - at least this is true for me. I wasn't surprised when the Lancet found mirtazapine to be one of the most effective ADs available. The problem is, I can only use it sparingly, as it quits working very quickly. This time around my doc told me to load up on fish oil and foliate because they may prevent poop out.
So you used the bead method to taper off Pristiq / Effexor? You must be very patient, lol. When I quit Effexor after ... 6 months?... I loaded up on Prozac and suffered from mild withdrawal for a few days - okay, the third day was atrocious but it was all over soon enough.
Why do you think FX was inferior? Didn't it buffer the withdrawal? According to my doc, the problem with Effexor is that it's a CYPD6 substrate. Just about anything can inhibit CYPD6 so the levels of venlafaxine and desvenlafaxine in your systen can vary very quickly. So Pristiq should be smoother... or so he claims. We'll see.
Re: sexual side effect. I don't know about you, but I resigned myself to chemical castration long ago. It's either that or suicidal depression. There's an advantage to imho, if you're single and looking for a partner you're not ruled by your.. genitalia lol.. and can actually get to know the person on another level first. It's been interesting. TMI info maybe but sildenafil is a complete bust for me.
I'm rambling as usual. Thanks LSman :)
poster:klein
thread:1064701
URL: http://www.dr-bob.org/babble/20140419/msgs/1064750.html