Posted by porkpiehat on April 5, 2014, at 15:21:02
In reply to Re: is there a drug that offsets buspar anger?? » porkpiehat, posted by SLS on April 5, 2014, at 14:35:25
> > I loved buspar for the first week (low dose plus SSRI). I could read, concentrate, make jokes, didn't feel social subordinated. Then insane anger kicked in.
> >
> > I'm reading that it's likely pp-1 metabolite stimulating alpha2 adrenoreceptors (antagonizing I think)
> >
> > http://www.dr-bob.org/cgi-bin/pb/mget.pl?post=/babble/20030604/msgs/232446.html
> >
> > I'd love to start buspar again...it even helped sexually if I can recall. Would there be a way to block this action?
> >
> > Please and thank you!
>
>
> You could try Brintellix (vortioxetine) instead. It is not a DA receptor antagonist. It does not produce 1-PP. It has SERT inhibition, 5-HT1a partial agonism, and 5-HT7 antagonism. It should have little, if any, sexual side effects. It is new.
>
>
> - ScottThat sounds exciting! My pdoc had mentioned it but was unsure of its efficacy this early on She did describe it as SSRI+buspar, however.
I notice that it is also a NE transporter blocker. Would that cause similar agitation? Wellbutrin, Zoloft, and serzone all incited anger in me also, if that's any indication
poster:porkpiehat
thread:1063701
URL: http://www.dr-bob.org/babble/20140328/msgs/1063705.html