Posted by bleauberry on March 21, 2014, at 10:45:05
In reply to Any good NRI's?, posted by Sac on March 18, 2014, at 18:55:55
There are various TCA's to try. But in my experience the best way to hit norepinephrine hard is with Savella. It has a ratio of 3:1, norepinephrine:serotonin. Cymbalta on the other hand is only 1 part norepinephrine to 30 parts serotonin. Effexor is 1:9, mostly serotonin.
I found that really small doses of Savella, as in 6mg or so roughly (custom home made doses) have a fairly pronounced and rapid norepinephrine boost, almost sort of similar to a smooth weaker version of ritalin maybe. I got the antidepressant "blahs" at higher doses of Savella. But at lower doses it was a nice norepinephrine boost that felt good.
poster:bleauberry
thread:1062739
URL: http://www.dr-bob.org/babble/20140307/msgs/1062942.html