Posted by Frequentfryer on March 18, 2014, at 22:26:08
In reply to Re: GABAnergics for TRD especially Socaial Anxiety, posted by phidippus on March 17, 2014, at 13:38:26
> I was going to suggest Tiagabine as I have taken it before. As a anxiolytic is a has amoderate to strong effect and helps with sleep greatly. Its basically a GABA reuptake inhibitor (SGRI), increasing the available amount of GABA in the brain.
>
> You can take anywhere from 2-56 mg and I have no idea the effects of higher doses as the most I ever took was 12 mg. The only notable effect was some 'drunkenness' that dissipated.
>
> EricCheers Eric!
Mmm. The drunkenness you describe sounds allot like Baclofen. I find Baclofen is the Closest thing to Alcohol in a pill. But if you take the right dose you get all the positives of Alcohol without the Negatives
Most people do not find this with Baclofen nor did I when I wasn't taking an MAOI. And Tiagabine is not very popular at all. But in combination with an MAOI it could work.
I wonder why there arn't more potent GABA reuptake inhibitors on the market. They could be awsome for Anxiety. Big $ to be made their.
poster:Frequentfryer
thread:1062627
URL: http://www.dr-bob.org/babble/20140307/msgs/1062754.html