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Re: off Cymbalta on to Parnate? » Elanor Roosevelt

Posted by SLS on February 25, 2014, at 14:51:23

In reply to off Cymbalta on to Parnate?, posted by Elanor Roosevelt on February 25, 2014, at 13:45:41

I think you should hook-up with a doctor who will treat you with high-dosage Parnate outright. If Dr. Stewart will not do this, he might refer you to someone who does. Patrick McGrath, perhaps?

Did Effexor or Pristiq help you more than Cymbalta did? What about trying Fetzima (levomilnacipran) or Brintellix (vortioxetine). I might choose to discontinue Parnate to try these two drugs. I am particularly interested in Brintellix because it is a 5-HT7 receptor antagonist.

Right now, I am having no luck with Latuda or Saphris in treating my bipolar depression. My guess is that the 5-HT7 antagonism makes me feel better initially, to be followed by a worsening due to NE alpha-2a receptor antagonism. Remeron makes me feel worse. It is also a NE alpha-2a receptor antagonist. So... If you feel better with Remeron and you have bipolar disorder or psychotic depression, you might do well with Latuda or Saphris. Did you try Viibryd or Abilify by any chance?

Sorry for the ramble.

Keep an eye on Phiddipus. He is currently trialling Brintellix.

Good luck with Parnate.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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