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Re: 7 days on Brintellix » phidippus

Posted by SLS on February 25, 2014, at 5:59:21

In reply to Re: 7 days on Brintellix » SLS, posted by phidippus on February 24, 2014, at 18:21:02

Hi Eric.

> What cascade of events follows the antagonism of the 5ht7 receptor and what neuropsychiatric effects does it have?
>
> Eric

I apologize for the delay.

5-HT7 antagonism (heteroreceptor) > 5-HT release inhibition (5-HT1a mediated) > dopamine efflux (PFC, hippocampus, nucleus accumbens).

You are going to find this WAY cool:

http://www.ncbi.nlm.nih.gov/pubmed/22415605

I REALLY hope Brintellix works. I am hopeful for you.


- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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