Posted by SLS on February 16, 2014, at 18:30:46
In reply to Re: Switching from Abilify to Latuda - Failed » SLS, posted by Bob on February 16, 2014, at 14:41:20
> > Well, Latuda was a failed treatment for me. Despite an encouraging improvement in symptoms during the first few days, Latuda made me feel very much worse over time and upon a dosage increase to 60 mg/day. I had to fight thoughts of suicide. Not fun. I have been feeling better since discontinuing Latuda two days ago. It is my suspicion that my bipolar depression was made worse by the ability of Latuda to block NE alpha-2a receptors. Other drugs with this property have exacerbated my depression in the past, including Remeron and idazoxan. My guess is that more people will profit from the 5-HT7 antagonism exerted by Latuda in the treatment of depression than will suffer an exacerbation of that illness.
> >
> > Good luck to everyone being treated with Latuda!
> So are you back on Abilify then?I have restarted Abilify using a loading dose of 30 mg to get things going. I am going to request of my doctor to try Saphris (asenapine). It is a fairly potent antagonist of 5-HT7 receptors - more so than Abilify. I might even lose weight on it.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1059698
URL: http://www.dr-bob.org/babble/20140214/msgs/1060763.html