Posted by rose45 on February 16, 2014, at 8:12:06
In reply to Re: nardil tolerance and ensuing cognitive problems, posted by phinxeezaDr on February 15, 2014, at 9:32:37
> > I was lucky. I took part in a couple of studies at the Psychopharmacology Dept,BRI in Bristol. Prof Nutt was leading the team there at the time, and seeing as I'd tried all the SSRIs I was 'recommended' phenelzine (Nardil). Worked a treat for 2yrs or so. At some point I was switched to Isocarboxazid (Marplan). 1st time I didn't like it. So went back to Nardil. Then I gave Marplan a second go with different addons and along with clonazepam my social anxiety was sorted. Just needed more of a mood boost, which I now have with my other meds.
> > And its worth mentioning that, from my experience most Psychiatrists & Psychopharmacologists tend to use the generic names when they're talking meds. Hence instead of Marplan they will call it isocarboxazid which is the actual name of the drug. Marplan is just a brand name and here in the UK they dont make 'Marplan' any more. Its turned generic. So you could have missed other meds your doc mentions simply coz you're unfamiliar with the generic names.
> > It was indeed hard to get hold of at one point which was very scarey. But the production seems fine again now.
> > One last thing to remember
>
> ignor that last line!
Yes, you were very lucky - do you live in Bristol, or did you go there in order to take part in the study ? Thank you for your information about marplan - I use the simpler names for typing, but Im well aware of the generic names - and definitely no doctor has ever suggested marplan/isocarboxazid to me. I suppose each doctor has their own treatment ideas. I had to insist on being switched to an maoi at the Chelsea and Westminster and I suggested parnate because my mother had been on it. My psychiatrist on the home treatment team there had never prescribed an maoi before, so he did as I suggested because I had been with them for approx. 6 months and was still suffering so much. And when I went to the Maudsley hospital for a second opinion, with Prof.Anthony Cleare, I asked him what I should do if the parnate ever stopped working, as the nardil had done. His answer was that I should increase the dose. He never mentioned anything about another maoi, and I have his opinion all in writing too!Actually parnate has far fewer side effects than the nardil did, and it began to work much faster too - the awful depression and anxiety lifted within 2-3 weeks, whereas with nardil, it always took 8 weeks of horrible suffering before I got relief. Parnate doesnt give you that 'high',or mood boost as you put it, but that may not be a bad thing for me. I was definitely more sociable when taking nardil, but also spending too much money, and a bit 'over the top', according to friends. I have been experimenting lately with going to bed much later, and not taking any sleep medication. I really feel so much better when I am taking less pills.(I take the entire parnate dose first thing in the morning). It has worked fairly ok for the last 2 nights, so I will continue and see how it works out. I do appreciate being able to share all this with others, because whatever doctors say or believe, it is only those who take the tablets who really know how it makes them feel.
poster:rose45
thread:1042294
URL: http://www.dr-bob.org/babble/20140214/msgs/1060748.html