Posted by jrbecker76 on February 14, 2014, at 10:32:10
In reply to Re: trazodone » sadperson, posted by phidippus on February 13, 2014, at 23:01:22
Trazodone and Nefazodone both increased my afternoon depression, anxiety and dysphoria. I believe it had to do with the metabolism of the parent drug into mCPP, a metabolite with a very anxiogenic and depressiogenic profile. Both of these drugs would be ideal as a good augmentor if it wasn't for that conversion. I also found that getting off both drugs was considerably difficult.
Just my take.
JB
poster:jrbecker76
thread:1060605
URL: http://www.dr-bob.org/babble/20140214/msgs/1060673.html