Posted by Christ_empowered on January 18, 2014, at 13:38:58
In reply to Re: SLS/anyone. Safest highest dose of Thorazine?, posted by rjlockhart37 on January 17, 2014, at 23:26:10
I did some googling. The atypicals are nicer, usually, than good ole thorazine, but they can still convert them into Thorazine (CPZ) units, just like the old ones.Its works like this: 100mgs/Thorazine=2mgs/Haldol= (according to my googling...)...75/Seroquel, 5/Zyprexa, 7.5 Abilify.
At high doses, Thorazine is the worst thing ever. At lower doses, the EPS is actually comparable to some of the atypials (remember, thorazine has an anti-cholinergic component, so that helps reduce EPS) and the dysphoria isn't so terrible. I seem to recall reading that akathisia is, however, still an issue at lower doses for some people.Anyway, like sigisimund said, I'd try 100 before you go popping a handful. In the US back in the day, docs would commonly go up into several hundreds, even above 1 gram, of Thorazine per day. Not surprisingly...bad things happened :-( Keep in mind, back then docs were taught that Parkinsonism was an important sign that the drug was working. Apparently, dull eyes, stiff gait, and tremor=successful treatment. Thank you, psychiatry.
I'd try, personally, to keep it at or under 300mgs/day. If I recall from "Mad in America" correctly (there was a lot of older literature in there), 300mgs/day was found to be quite useful in "ambulatory" outpatients in the UK and parts of Europe. For whatever reasons (probably cultural), American docs had a tendency to ramp up the doses considerably, especially on poor inpatients.
Good luck!
poster:Christ_empowered
thread:1058852
URL: http://www.dr-bob.org/babble/20140104/msgs/1058910.html