Posted by bleauberry on January 11, 2014, at 5:52:58
In reply to Combining SSRI with alt AD after poop-out?, posted by SpratNZ on January 11, 2014, at 3:52:25
Antipsychotics are a good idea to revive a pooped out ssri, especially either abilify or zyprexa. Zyprexa brought new life to my prozac some years ago and lasted 8 years total.
The best way to keep an ssri going, in my opinion anyway, just based on my own observations, is to add a TCA antidepressant.
Nortriptyline is usually a first choice. Desipramine possible.Savella sort of does the same thing, all in one, but I prefer the multi-angle multi-mechanism approach of the SSRI+TCA better, because I believe it has the potential to be more thorough, and you can adjust the doses of both sides of the equation separately.
Anyway, poop out is a common problem and I am really sorry you are experiencing that. 25 years in 3 year chunks. Not bad. You did pretty good actually compared to some other people. I think once you decide what to do you will get some more good years. I'm not sure there is any way to totally prevent poop out, because our brains are constantly changing, in motion, not static, and the genes are always going to attempt to do what their original instructions were, which is going to involve somehow undoing whatever the med molecule is doing. It's a foreign uninvited intruder as far as the genes are concerned.
Some people have gone 10 years or more on either zoloft or prozac, so poop out doesn't always happen.
poster:bleauberry
thread:1058250
URL: http://www.dr-bob.org/babble/20140104/msgs/1058254.html