Posted by bleauberry on January 10, 2014, at 9:25:38
I've been coming to pbabble for a really long time....somewhere in the 20 to 25 year range. I was here way back in the beginning. I have seen a lot here.
Based purely on what my own eyes have seen in the posts of pbabble over a period of about 20 years, this is the order of effectiveness of antidepressants.
Best: Nardil, Parnate.
Second Best: SSRI + AP combinations
Third Best: SSRI + stimulant combinations
Fourth Best: SSRI + TCA combinationsWorst: Mono SSRIs, mono TCAs.
Oddball meds such as Remeron fall somewhere in the middle.
These observations do not jive with clinical studies, which show pretty much the same results from one approach to another, plus or minus a few percentage points.
Despite what my eyes have seen, I tend to buck the trend and favor the SSRI + TCA route. Honestly, I wish everyone would receive Nardil or Parnate as first line therapy. That would save a ton of money and suffering. I think the risks are overblown in such a way that deserving patients never get the chance.
What have you observed on this board that seems....generally speaking...the most effective routes for a general population to pursue in terms of psych med choices?
poster:bleauberry
thread:1058183
URL: http://www.dr-bob.org/babble/20140104/msgs/1058183.html