Posted by Hugh on January 5, 2014, at 13:56:14
In reply to Re: LDN (low dose naltrexone)? (Hugh?), posted by baseball55 on January 4, 2014, at 22:08:43
This is from http://www.ldnscience.org/low-dose-naltrexone/how-does-ldn-work
Naltrexone is an externally administered drug that binds to opioid receptors. In doing so, it displaces the endorphins which were previously bound to the receptors. Specifically, by binding to the OGF [Opioid Growth Factor] receptor, it displaces the bodys naturally produced OGF.
As a consequence of this displacement, the affected cells become deficient in OGF and three things happen:
Receptor production is increased, in order to try to capture more OGF.
Receptor sensitivity is increased, also to try to capture more OGF.
Production of OGF is increased, in order to compensate for the perceived shortage of OGF.Since LDN blocks the OGF receptors only for a few hours before it is naturally excreted, what results is a rebound effect; in which both the production and utilization of OGF is greatly increased. Once the LDN has been metabolized, the elevated endorphins produced as a result of the rebound effect can now interact with the more-sensitive and more-plentiful receptors and assist in regulating cell growth and immunity.
poster:Hugh
thread:1057516
URL: http://www.dr-bob.org/babble/20140104/msgs/1057867.html