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Re: buprenorphine » g_g_g_unit

Posted by doxogenic boy on November 16, 2013, at 17:57:49

In reply to Re: buprenorphine » doxogenic boy, posted by g_g_g_unit on November 16, 2013, at 9:24:42

>So you believe you were in a protracted state of withdrawal for 5 years?

The condition may have become self-sustained after some time, but I am sure that buprenorphine caused it. I have never had so extreme and constant anxiety and severe depression before for so long time. (I have been depressed and had GAD (and OCD) many for years before this, but not to this extreme extent.)

See also this message:
http://www.dr-bob.org/babble/20070219/msgs/734560.html
Quote
"I don't think anything can compare with the black depression that can arise when the opiates fail. It could be three months. Three years. Maybe never, if you're lucky. But the body eventually can't function with them, and you go into withdrawal, even when on a stable dose. At least I can say it happens, because it happened to me."
End quote

> What led your doctor to prescribe buprenorphine in the first place?

I had tried "everything", and I was desperate. I showed him information from the net, such as this:
https://web.archive.org/web/20100505195605/http://balder.prohosting.com/~adhpage/bupe.html

I have tried Xyrem too, with no antidepressant effect.

>I have read that combining buprenorphine with low-dose naltrexone will block the mu-agonism and isolate the kappa-antagonism, which is what I'm interested in. That might eliminate some of the side-effects and addiction potential. Of course, getting a doctor to prescribe buprenorphine at all is another matter.

It was mentioned something about a combo with buprenorpine in a post recently.
http://www.dr-bob.org/babble/20130930/msgs/1052097.html
Quote:
"ALKS 5461/ Samidorphan-Buprenorphine combo - fast tracked for MDD. Seems fairly novel, a combo of μ-opioid antagonist and mu agonist."
End quote.

>I have searched the Australian directory of psychiatrists for those who treat anxiety AND substance abuse and who are listed as having experience in opiate agonists. Would emailing them be the best bet?

I don't know, I live in Norway. But email is good for such purposes, I have got answers from politicians in the Norwegian parliament via email.

- doxogenic


Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine


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poster:doxogenic boy thread:1054468
URL: http://www.dr-bob.org/babble/20131115/msgs/1054503.html