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Re: Low dose naltrexone with SSRI for anhedonia

Posted by sk85 on October 30, 2013, at 4:49:11

In reply to Re: Low dose naltrexone with SSRI for anhedonia » sk85, posted by g_g_g_unit on October 16, 2013, at 4:16:12

I'm getting pretty decent results for anhedonia with 0,5 mg of NTX taken 1 h before bedtime (at 2 weeks currently). I also lowered my sertraline from 50 to 25 mg (which has been shown to still provide benefits but significantly lowered incidence of SEs). However I tried going higher with the NTX and the insomnia was exhausting and I decided I'm might be way too greedy and should perhaps satisfy with 500 ug results where my sleep is fine.
Other effects noticed: appetite lowered, libido hightened, slightly oppositional when communicating with other people, OCD might be slightly increased, also slight anxiety maybe, no increased AD effects but (as said before) ability to "enjoy" things has improved, decreased desire for caffeine.
Will continue to see how things evolve, however, subjectively it's having neutral/positive effects for many different aspects of my emotional state.

Ikaros

> I was interested in LDN for anhedonia and did a little bit of research into people's experiences.
>
> Cost-wise, it seems harmless, since if you obtain Naltrexone online and produce your own solution, it's like $50 for a year's supply.
>
> The thing that stood out was that some people emphasized titrating slowly and essentially treating it like an SSRI .. i.e. being careful with how you move up can allow you to side-step most of the side-effects like insomnia. There were suggestions, however, that some tolerance did set in w/r/t it's opiate-like properties, and that people became lazy/numb with consistent use, as you would with a regular opiate. It seemed like that effect could be dodged with lower/increasing the dose regularly, but I couldn't find anything concrete in that regard.
>
> Have you thought about something like Mirapex? or too risky?


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