Posted by SLS on October 23, 2013, at 6:47:49
In reply to Re: Do antidepressants worsen your depression? » SLS, posted by Bob on October 22, 2013, at 21:33:25
> > Generally speaking, I see no reason to dispute the existence of these adverse effects. My only caveat is that untreated depressive disorders tend to get worse over time naturally. I only skimmed your post, so I didn't see any methodologies that take this into consideration.
> >
> > More study. More open minds.
> >
> > Thanks for posting this.
> >
> > Some antidepressants exacerbate my depression to the point of producing suicidality. Tachyphylaxis is very dramatic with me. I experience a robust antidepressant effect for about 3 days before relapsing.
> >
> >
> > - Scott> I have tried many treatments where there is an antidepressant effect literally for about a day or only hours.
Me, too! Literally hours! It is a terrible disappointment when relapse occurs. Have you ever seen the movie "Awakenings"?
> This has gotten much more common and more severe in recent years. My response to psychiatric drugs is very different than when I first tried them about 20 years ago.
>
> BobI have no doubt that exposure to antidepressants leaves the brain changed in some way. That "poop-out" occurs at all is evidence of this. Perhaps one change involves the downregulation of serotonin autoreceptors. This could explain the development of a hypersensitivity and intolerance to a SSRI drug after it is discontinued for an extended period of time. If a case history demonstrates extremely chronic or recurrent depression, it is a good idea to consider indefinite treatment to prevent treatment resistance.
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Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1052784
URL: http://www.dr-bob.org/babble/20130930/msgs/1052860.html