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The Myth of Neurogenesis?

Posted by doxogenic boy on September 25, 2013, at 16:39:11

Is neurogenesis in adult primates a myth? It says so in the article below. Have any of you heard of this before?

http://bipolarnews.org/?p=1949

Excerpt:

The Myth of Neurogenesis in Adult Primates Debunked
July 22, 2013 · Posted in Neurobiology


In a plenary lecture at the Collegium Internationale Neuro-Psychopharmacologicum (CINP) in Istanbul in 2012, Pasco Rakic, professor of neuroanatomy at Yale University, may have debunked a myth of modern medicine, one that we have cited in many previous BNNs. Despite what has been written by famous neuroscientists and published in the most prestigious journals, including Science, Cell, and PNAS, based on data in rodents, Rakic presented evidence that neurogenesis does not occur to any substantial extent in adult primates.
[...]
However, on the positive side, the mood stabilizers (lithium, lamotrigine, valproate, and carbamazepine) and some atypical antipsychotics prevent episodes and increase the neuroprotective factor BDNF, or brain-derived neurotrophic factor, which facilitates synaptogenesis and helps protect neurons. BDNF is produced in selected neurons in the brain and decreases with stress and affective episodes, further endangering neurons.
--------
See also my post about brain volume and antipsychotics:
http://www.dr-bob.org/babble/20130828/msgs/1051297.html

- doxogenic


Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine


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poster:doxogenic boy thread:1051299
URL: http://www.dr-bob.org/babble/20130828/msgs/1051299.html