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Low testosterone level - medication-induced?

Posted by doxogenic boy on September 22, 2013, at 17:58:58

Hello,
I have recently got the results of a lot of blood tests I took, some of them to check that my liver is ok because of the agomelatine, which it is. But the tests showed that I have low testosterone levels, the lowest I have ever had.

The normal range for testosterone is from 6,7 to 31,9,(I don't know what unit of measurement it is) and my testosterone level is 5,9. Also the luteinizing hormone is low.
( http://en.wikipedia.org/wiki/Luteinizing_hormone )

Could this be medication induced, and is it due to some of the drugs, or because of the combo as a whole, and its interactions? (See my meds in my signature below.)

I have no sexual desire, but I have experienced that also when I have been medication free. I am not depressed now.

Should I use testosterone injections to combat the lack of sexual desire, or can testosteron injections cause depression in the long run? Have any of you got low testosterone levels because of your meds? (It can happen to both men and women.)

Are there other hormones I should check with blood tests? My psychiatrist suspect high cortisol levels, and I probably will take blood tests for that, but how can cortisol levels be high when I feel calm and euthymic?

My former doctor prescribed testosterone injections in 2001/2002, and it had some effect for my libido, but it lost its effect completely when my depression worsened April 2002 because of a breakup.

Here is the article "Antidepressant-Induced Sexual Dysfunction Associated with Low Serum Free Testosterone":
http://www.mental-health-today.com/rx/testos.htm

Excerpt:
In the course of an evaluation for treatment of antidepressant induced sexual dysfunction (ASD) with a new agent, an unforeseen pattern emerged in the pre-treatment laboratory assessment. Free serum testosterone levels in both men and women study subjects were found to be below the normal ranges in 75 percent of subjects in this small study. There were no other consistent laboratory findings that could account for such a high percentage correlation. Further inquiries into the possible causes for decreased serum testosterone and its association with ASD seems warranted.
--------------------

I would greatly appreciate any response to my questions above.

- doxogenic


Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine


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poster:doxogenic boy thread:1051148
URL: http://www.dr-bob.org/babble/20130828/msgs/1051148.html