Posted by alexandra_k on September 12, 2013, at 5:04:48
In reply to Re: Blood Type association, posted by alexandra_k on September 7, 2013, at 1:07:59
someone said 'it is easy to tell the brains of schizophrenics - theirs are the brains that look normal'. i'm starting to think that the same thing applies to the genetics of mental disorder. easy to tell. the ones that look normal.
i've been learning...
i remember finding a couple studies a few years back on the iceland genome project. it was a big (big big) deal because of the extensive records that had been kept over successive generations. some stuff on mental disorder... i showed it to some biology people... had a reading group on it... and they kind of scrunched up their noses. said that the findings were statistically significant... but only just. Given error margins...
the National Institute of Mental Health (NIMH) has introduced the Research Domain Criterion (RDC) which is an attempt at an alternative classification system from the DSM. They are trying to carve up categories that might turn out to map onto specific brain pathologies and to map onto specific genes. Because... After years of research and millions of dollars of funding our understanding of DSM diagnostic categories hasn't gotten us particularly far. DSM is still used clinically (for health insurance). But the future of psychiatry... Will be in some future version of the RDC categories... As they eventually manage to revise the categories into validated kinds (with behavioral profile mapping to neurobiology mapping to genes).
> Still being developed, the RDoC system began with five broad domains of psychological function that appear especially ripe for integration with recent developments in neuroscience. In addition to social processes, these are cognitive systems (attention, perception, working memory), positive valence systems (reward, appetitive behaviors), negative valence systems (depression, defeat, loss), and arousal-regulatory systems (activity, sleep, rhythms).
http://www.nimh.nih.gov/about/director/2012/research-domain-criteria-rdoc.shtml
poster:alexandra_k
thread:1050240
URL: http://www.dr-bob.org/babble/20130828/msgs/1050507.html