Posted by SLS on July 25, 2013, at 16:08:49
In reply to Re: Doing a fair bit better, posted by Lamdage22 on July 25, 2013, at 7:03:42
From what little I have seen, quetiapine (Seroquel) has more therapeutic activity at 400 mg/day than it does at 300 mg/day. Take that with a grain or two of salt, though. For depression, it might be that the norquetiapine metabolite is important, as it is a NE reuptake inhibitor. If the doctors are aware of this, they would be even more cautious to give you tranylcypromine.
I say, let the doctors do their thing. Tell them that you would like to work *with* them to establish a treatment plan. Nothing you say to them is going to change their minds about the tranylcypromine if they are scared to use it in the first place. At least you will find out how high they are willing to go as a maximum dosage and how rapidly you can get there with a titration schedule. I don't think that you have much of a choice. Just ask them to please explain to you how they arrived at their clinical decisions.
It is frustrating.
I participated in a series of double-blind drug trials at the US NIH as an inpatient. It was necessary for me to give my doctors consent to treat me for 9 months without disclosing to me what they were giving to me.
A year from now, it won't matter whether they started you at 10 mg/day or 30 mg/day. There are some doctors who would never treat you with tranylcypromine at all, even if you begged them. As Tomatheus so insightfully pointed out, your doctors might be looking at your frustration and displays of anger as signs that the tranylcypromine is triggering a manic or psychotic episode. Be strategic in your use of words. Exercise as much patience as you can.
I really want to see you get well. I might be wrong, and I might not tell you the things that you want to hear, but I do care.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1047402
URL: http://www.dr-bob.org/babble/20130706/msgs/1047793.html