Posted by SLS on July 14, 2013, at 5:11:30
In reply to Re: Does Apathy Ever Go Away? » SLS, posted by Hugh on July 13, 2013, at 10:21:21
> > Do you think that you would respond to baclofen were you to restart it?
>
> The dose that had the remarkable antidepressant, anti-anxiety effect on me was 75-100 mg. But after a week on this dose, I couldn't sleep anymore. I was up for over fifty hours straight when I decided to stop taking it. After it cleared my system and I could sleep again, I started taking it again, and slowly increased my dose over the next few weeks. I got up to 37.5 mg when it started to aggravate my mitral valve prolapse. It wasn't helping my depression or anxiety at this dose, so I decided to abandon it. But I'm extremely sensitive to many drugs and supplements. I think most people could tolerate those doses of baclofen without those side effects. Baclofen increases striatal levels of dopamine. Maybe that's why it worked so well for me, for a while, and why it caused insomnia.I hate hearing that someone responds well to a treatment, only to give up on it due to the appearance of insomnia. The only time I responded robustly for an extended period of time, I developed severe insomnia. Rather than discontinue treatment, the doctor had me combine two benzodiazepines: Ativan and Halcion. I slept well and maintained a remission of depression. Halcion will knock you out. Ativan will help keep you asleep. I doubt that very many doctors will prescribe Halcion anymore. Ambien might be an effective replacement to be combined with Ativan. I do not know how safe such a combination would be, though.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1046180
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