Posted by tecknohed on May 28, 2013, at 20:15:36
In reply to Re: Marplan winning combo! » tecknohed, posted by SLS on May 28, 2013, at 19:36:08
> > I have just found relief from the following each day: 90mg isocarboxazid, 4mg clonazepam, 300mg bupropion, 50mg quetiapine and the last added was Amitryptyline 100mg
>
> That's a very interesting combination. I am surprised that your doctor consented to treat you with it.Well, my pdoc at the time (Professor David Nutt), who ran the outpatient psych clinic became my pdoc when the rest of his team were somewhat uncomfortable with my suggestions and med responses, They put me with the big man. He's great. Lovely personality. And essentially he knew I was only there for meds & med-talk. If I wanted councelling I'll go to a councello/therapist. I like things kept seperate. It was when I reminded him that studies with NRIs show that they infact protect from hypertensive crises, as NRIs have a protecting effect against hypertensive crises. One study was with tranylcypromine + reboxetine. Mice or Rat study.
>
> I am particularly interested in the addition of amitriptyline and bupropion. How do you know that the bupropion is helping?The bupropion Gets me outa bed in the morning, giving great steady energy levels. And I can 'feel' its dopaminergic effects. And with the low dose quetiapine compliments the DA effects of bupropion. Thats how it feels.
And I stopped drinking totally about a month before the amyltryptamine kicked in.> What has occurred with the addition of amitriptyline that produced such a great antidepressant effect?
Hard question. All I can think of is that because of the length I've been depressed and the severety this time round, once started amitryptamine just kicked in after a very delayed response. I've knew an old friends sister who was on Prozac about 3 months before it kicked in.
> Thanks.
>
> I hope your response to treatment is long-lasting.
>
>
> - ScottThankyou!
poster:tecknohed
thread:937777
URL: http://www.dr-bob.org/babble/20130527/msgs/1044434.html