Posted by SLS on May 8, 2013, at 17:23:36
In reply to Re: Optimal Parnate Dosing times, posted by vanvog on May 8, 2013, at 15:26:41
> > > Indeed it is probably possible to take it on alternate days.
> >
> > This has not been true in my case. As a matter of fact, if I miss a single dose, I experience REM rebound that night along with feeling noticeably worse the next day.
>
>
> I think Gillmann is referring to MAO inhibition effect of Parnate and MAO inhibition ONLY in this sentence. He is probably right.
>
> Please read the second paragraph I posted again.I still find it difficult to believe that dosing Parnate every other day would work unless the dosage were very high. Speaking for myself only, I relapse after 48 hours of a 10 mg/day reduction in dosage. Would that be an indicator of a recovery of MAO activity?
The half-time of MAO recovery has been reported to be 3.6 days in the brain.
http://link.springer.com/article/10.1007%2FBF00508078
How many people are you aware of who dose Parnate every other day?
I'm not buying it.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1043363
URL: http://www.dr-bob.org/babble/20130501/msgs/1043412.html